U.S. Senator Mary Cantwell is urging Secretary of State Hillary Clinton to help American college student Amanda Knox, who was convicted of murdering her study abroad roommate in Italy and sentenced to 26 years in prison. Senator Cantwell, who represents Knox’s home state, has issued a statement saying she has profound concerns that Knox has been failed by the Italian justice system.

Also tonight: science, skepticism and allegations of conspiracy. World leaders have gathered in Copenhagen for the United Nations climate summit but leaked emails from an internationally-renowned climate research unit are threatening to overshadow the talks.

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Tonight on 360°, an American convicted of murder in Italy. Friends and family of Amanda Knox speak out. Hear why they're outraged at the jury's decision. Plus, another mistake uncovered in the Maurice Clemmons case. He's the man who shot to death four cops in Washington State. And, Hillary Clinton talks about her role – Mother of the Bride.

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Who dropped the ball in the Maurice Clemmons case? He's the man who shot and killed four cops in Washington State over the weekend. There is new evidence tonight that Washington state tried to keep Clemmons behind bars. But they ran into resistance from Arkansas. We're keeping them honest.

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Tonight on 360°, a prime-time exclusive on the war in Afghanistan. Anderson will talk Gen. David Petraeus, who is the chief of U.S. Central Command. There's a lot of pushback to the strategy on Capitol Hill. We'll talk it over with a group of reporters who've sent time on the ground in the war zone and know firsthand what's at stake.

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Tonight on 360°, Pres. Obama's decision on Afghanistan. He's adding an additional 30,000 U.S. troops to the region and wants to start getting all American forces back home in July 2011. We've got the raw politics and the raw numbers. We'll talk about the new strategy with an impressive panel of experts. And we want to hear from you.

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Tonight, we have breaking news on the hunt in Washington state for the gunman accused of killing four police officers. Plus, new details on the White House party crashers. The Washington Post is reporting on e-mails that the couple says clears them of wrongdoing. We have the White House reaction.

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Tonight on 360°, the photo the Secret Service must hate to see. It shows President Obama face-to-face with the White House party crashers. Plus, the latest on Tiger Woods' SUV accident. Why his wife used a golf club in the incident and why police faced when they got on the scene. Plus, meet the CNN Hero of the Year.

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Tonight on 360°, the security breach at the White House state dinner. We're also digging deeper on Pres. Obama's decision to boost U.S. forces in Afghanistan and meet a CNN Hero.

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Pres. Obama and the First Lady hold their first state dinner at the White House. We'll go up close and look at the raw politics of the visit. Plus, nip, tuck and tax. Could a so-called "botax" on plastic surgery help pay for health care reform. We're keeping them honest.

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Tonight on 360°, could a government panel's guidelines influence the law over what would be covered in the Senate health care reform bill? We're keeping them honest on Capitol Hill. Plus, former Vice President Dick Cheney speaks out against the 9/11 terror trials in New York. And, a bank robbery suspect is arrested by cops. And wait till you see what was caught on tape as he was handcuffed.

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